A key forensic lead in the disappearance of Nancy Guthrie has not produced the breakthrough investigators had hoped for. Chris Nanos said DNA recovered from a glove found about two miles from Guthrie’s home was submitted to the Federal Bureau of Investigation database but did not generate a match.
According to Nanos, the unknown male DNA profile was entered into the FBI’s Combined DNA Index System (CODIS). However, the search returned no matches. Authorities have emphasized that while this result may slow the process, it does not rule out future developments, as new DNA profiles are regularly added to the national system.
Investigators previously said forensic testing linked the male DNA profile from the glove to a masked individual seen on surveillance video outside Guthrie’s home in the Catalina Foothills during the early morning hours of Feb. 1. The individual was reportedly seen near the property around the time the 84-year-old woman was reported missing. Officials have also stated that DNA collected inside the residence was tested through CODIS and similarly produced no matches.
The case has drawn national attention because Nancy Guthrie is the mother of Savannah Guthrie, co-anchor of Today. Authorities have confirmed that blood matching Nancy Guthrie’s DNA was found on her property, and investigators continue to examine evidence. Family members have been publicly cleared by law enforcement and described as cooperative throughout the investigation.
Officials say the investigation remains active. The FBI and the Pima County Sheriff’s Department are asking anyone with information to come forward. A reward of up to $100,000 is being offered for information leading to her location or to an arrest and conviction in connection with the case. Law enforcement representatives have indicated that additional investigative efforts are ongoing, and they remain hopeful that new information will emerge.